当归素

产品编号：Y3283
英文名称：Angelicin
CAS号 523-50-2  
分析标准品
分子式 C11H6O3 分子量186.16

基本信息:

敏感性 对热敏感
密度 1.389
溶解性 Soluble in Chloroform and Methanol
存贮条件 储存温度：2-8°C
描述 
别名 异补骨脂素;2H-氟[2,3-h]色满-2-酮;氟[2,3-h]苯并吡喃-2-酮;Furo[2,3-h]benzopyran-2-one;2H-Furo[2,3-h]chromen-2-one;Isopsoralen; 2-Oxo-(2H)-furo(2,3-h)-1-benzopyran
生化机理 Angular furocoumarin with diverse photobiological effects. Upon long-wavelength UV irradiation, forms monoadduct with double-stranded DNA and reacts with unsaturated fatty acids. Inhibits DNA and RNA synthesis and cell replication in Ehrlich ascites tumor cells.
应用 An angular furocoumarin, may be used as a photoactivatable molecule that reacts with DNA and unsaturated fatty acids to form monoadducts. Angelicin may be studied as a potential phototherapeutic and to understand its mechanisms of action and effects on RNA and DNA synthesis.