伊维茵素

产品编号：Y0698

英文名称：Ivermectine

CAS号 70288-86-7

分析标准品

分子式 C48H74O14 分子量875.09

基本信息:

存贮条件储存温度 2-8°C

描述

产品介绍稳定，在水中溶解度极低。

别名MK-933;MK-933;22,23-Dihydroavermectin B1

生化机理

Ivermectin (22,23-dihydroavermectin B1a + 22,23-dihydroavermectin B1b) is a broad-spectrum antiparasitic avermectin medicine. Ivermectin is positive allosteric modulator of the α7 neuronal nicotinic acetylcholine receptor and the purinergic P2X4 receptor. Antihelmintic. Ivermectin also modulates glutamate- and GABA-activated chloride channels. Ivermectin potentiates glycine-gated currents at low concentrations (30 nM).

应用Positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptor; also modulates glutamate-GABA-activated chloride channels.