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英文名称 Anti-BDP/ARID3B
中文名称： 神经母细胞瘤相关蛋白ARID3B抗体
别 名 ARI3B_HUMAN; ARID domain containing protein 3B; ARID domain-containing protein 3B; Arid3b; AT rich interactive domain 3B BRIGHT like; AT rich interactive domain containing protein 3B; AT-rich interactive domain-containing protein 3B; Bright and dead ringer gene product homologous protein Bdp; Bright and dead ringer protein; Bright like; Bright-like protein; Brightlike; DRIL2.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Horse, Rabbit
产品类型 一抗
研究领域 肿瘤 发育生物学 神经生物学 干细胞 细胞周期蛋白 表观遗传学
蛋白分子量 predicted molecular weight: 61kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human BDP/ARID3B
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 ARID3B represents a member of a unique family of DNA-binding proteins that have roles in cell lineage gene regulation, cell cycle control, embryonic patterning and transcriptional regulation. ARID3B localizes to the nucleus and contains an AT-rich interactive domain (ARID) which has DNA-binding capabilities. Functioning as a transcription factor, ARID3B associates in a heterodimer with the related protein ARID3A and is believed to play an important role in neural crest survival during embryogenesis. In addition, ARID3B may participate in malignant transformation and neuroblastoma growth, suggesting a possible use of ARID3B as a tumor marker for neuroblastoma.
Function : Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A.
Subunit : Heterodimer with ARID3A. Interacts with unphosphorylated RB1.
Subcellular Location : Nucleus.
Tissue Specificity : Expressed in placenta, testis and leukocytes. Expressed in neuroblastoma. Present in K562 erythrocytic leukemia cells (at protein level).
Similarity : Contains 1 ARID domain.
Contains 1 REKLES domain.
Database links : UniProtKB/Swiss-Prot: Q8IVW6.2
中文名称： 神经母细胞瘤相关蛋白ARID3B抗体
别 名 ARI3B_HUMAN; ARID domain containing protein 3B; ARID domain-containing protein 3B; Arid3b; AT rich interactive domain 3B BRIGHT like; AT rich interactive domain containing protein 3B; AT-rich interactive domain-containing protein 3B; Bright and dead ringer gene product homologous protein Bdp; Bright and dead ringer protein; Bright like; Bright-like protein; Brightlike; DRIL2.
详细介绍：
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Horse, Rabbit
产品类型 一抗
研究领域 肿瘤 发育生物学 神经生物学 干细胞 细胞周期蛋白 表观遗传学
蛋白分子量 predicted molecular weight: 61kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human BDP/ARID3B
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
相关资料：
产品介绍 ARID3B represents a member of a unique family of DNA-binding proteins that have roles in cell lineage gene regulation, cell cycle control, embryonic patterning and transcriptional regulation. ARID3B localizes to the nucleus and contains an AT-rich interactive domain (ARID) which has DNA-binding capabilities. Functioning as a transcription factor, ARID3B associates in a heterodimer with the related protein ARID3A and is believed to play an important role in neural crest survival during embryogenesis. In addition, ARID3B may participate in malignant transformation and neuroblastoma growth, suggesting a possible use of ARID3B as a tumor marker for neuroblastoma.
Function : Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A.
Subunit : Heterodimer with ARID3A. Interacts with unphosphorylated RB1.
Subcellular Location : Nucleus.
Tissue Specificity : Expressed in placenta, testis and leukocytes. Expressed in neuroblastoma. Present in K562 erythrocytic leukemia cells (at protein level).
Similarity : Contains 1 ARID domain.
Contains 1 REKLES domain.
Database links : UniProtKB/Swiss-Prot: Q8IVW6.2
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