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FITC标记的肌萎缩侧索硬化症相关蛋白3抗体

文字:[大][中][小] 2017-5-2    浏览次数:908    

                                     FITC标记的肌萎缩侧索硬化症相关蛋白3抗体                                                                                                                                                
英文名称Anti-ALS2CR3/FITC
中文名称:FITC标记的肌萎缩侧索硬化症相关蛋白3抗体
别    名ALS2CR3; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein;TRAK2_HUMAN; Trafficking kinesin-binding protein 2.  

详细介绍:


规格:100ul 
说 明 书100ul  
研究领域细胞生物  神经生物学  Alzheimer's  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Sheep, 
产品应用ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量101kDa
性    状Lyophilized or Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ALS2CR3 (701-800aa)
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

相关资料:


产品介绍background:
ALS2CR3 may regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR

Function:
May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR 

Subunit:
Interacts with GABA-A receptor and O-GlcNAc transferase. Interacts with HGS (By similarity). Interacts with RHOT1/Miro-1 and RHOT2/Miro-2.

Subcellular Location:
Cytoplasm (By similarity). Early endosome (By similarity). Mitochondrion (By similarity). Note=Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner

Tissue Specificity:
Widely expressed, with highest expression in heart.

Post-translational modifications:
O-glycosylated

Similarity:
Contains 1 HAP1 N-terminal domain.

Database links:
UniProtKB/Swiss-Prot: O60296.2

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