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标记一抗
英文名称Anti-AFF4/FITC
中文名称:FITC标记的淋巴细胞相关AF4样蛋白抗体
别 名Alf4; Laf4; MGC107469; AF4/FMR2 family member 4; AF5Q31; ALL1 fused gene from chromosome 5q31; HSPC092; Lymphoid nuclear protein related to AF4 like; Major CDK9 elongation factor associated protein; MCEF; RP23-226J16.7; AFF4_HUMAN.
规格:100ul
说 明 书100ul
研究领域细胞生物 信号转导 细胞周期蛋白 转录调节因子
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep,
产品应用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量127kDa
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human AFF4
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍background:
May play a role in transcriptional regulation. Component of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor b (P-TEFb).
Function:
May play a role in transcriptional regulation.
Subunit:
Component of the cyclin-dependent kinase pair(CDK9/cyclin-T1) complex, also called positive transcriptionelongation factor b (P-TEFb).
Subcellular Location:
Nucleus.
Tissue Specificity:
Ubiquitously expressed. Strongly expressed inheart, placenta, skeletal muscle, pancreas and to a lower extent inbrain.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR. [DISEASE] Note=A chromosomal aberration involving AFF4 is found inacute lymphoblastic leukemia (ALL). Insertion ins(5;11)(q31;q13q23)that forms a MLL-AFF4 fusion protein.
中文名称:FITC标记的淋巴细胞相关AF4样蛋白抗体
别 名Alf4; Laf4; MGC107469; AF4/FMR2 family member 4; AF5Q31; ALL1 fused gene from chromosome 5q31; HSPC092; Lymphoid nuclear protein related to AF4 like; Major CDK9 elongation factor associated protein; MCEF; RP23-226J16.7; AFF4_HUMAN.
详细介绍：
规格:100ul
说 明 书100ul
研究领域细胞生物 信号转导 细胞周期蛋白 转录调节因子
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep,
产品应用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量127kDa
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human AFF4
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相关资料：
产品介绍background:
May play a role in transcriptional regulation. Component of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor b (P-TEFb).
Function:
May play a role in transcriptional regulation.
Subunit:
Component of the cyclin-dependent kinase pair(CDK9/cyclin-T1) complex, also called positive transcriptionelongation factor b (P-TEFb).
Subcellular Location:
Nucleus.
Tissue Specificity:
Ubiquitously expressed. Strongly expressed inheart, placenta, skeletal muscle, pancreas and to a lower extent inbrain.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR. [DISEASE] Note=A chromosomal aberration involving AFF4 is found inacute lymphoblastic leukemia (ALL). Insertion ins(5;11)(q31;q13q23)that forms a MLL-AFF4 fusion protein.
