吴茱萸内酯

英文名称：Evodine  
CAS号：1180-71-8
分析标准品,>98%(HPLC)  
分子式 C26H30O8 分子量470.51  

基本信息:

密度  1.39
熔点   271-272°C
存贮条件   储存温度2-8°C
描述  
产品介绍   柠檬苦素是一种三萜苷元(triterpenoid aglycone),来自于柑桔类水果.
别名   吴茱萸内酯 ;柠檬苦素;Limonin Limonoic acid 3,19:16,17 dilactone
生化机理  
Limonin is a triterpenoid aglycone that is a bitter principle of citrus fruits. Limonin is chemically induced carcinogenesis inhibitor and HIV-1 replication inhibitor. Limonin has anti-proliferative, proapoptotic activity on several cancer cell lines and inhibits azoxymethane-induced colon cancer in rats. Limonin also inhibits HIV-1 replication in culturedf monocytes, macrophages, and mononuclear cells, perhaps by inhibition of HIV-1 protease activity.  
应用   对几个肿瘤细胞系具有抗增殖、抗凋亡活性，并抑制氧化偶氮甲烷（azoxymethane）诱发的大鼠结肠癌。依靠抑制HIV - 1蛋白酶活性，抑制HIV - 1病毒在单核细胞，巨噬细胞和单核细胞的复制，