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中药标准品
|
产品编号 |
英文名称 |
CAS号 |
包装 |
|
Y3710 |
Curcumin |
458-37-7 |
可根据客户要求订制 |
产品编号：Y3710
英文名称：Curcumin
CAS号：458-37-7分析标准品
分子式 C21H20O6 分子量368.38
基本信息:
属性
密度 0.93
熔点 183°C
描述
产品介绍 易溶于冰乙酸，能溶于醇，不溶于醚带淡绿色荧先，溶于碱呈红棕色，加酸于碱液后变为淡黄色并析出姜黄素沉淀，溶于浓硫酸带黄红色，不溶于水。
别名 克扣明;姜黄色素;川芎内酯 B;1,7-双(4-羟基-3-甲氧基苯基)-1,6-庚二烯-3,5-二酮;(E,E)-1,7-双(4-羟基-3-甲氧基苯基)-1,6-庚二烯-3,5-二酮;Natural Yellow 3;Diferuloylmethane;Diferulylmethane;(E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
生化机理
Description:
IC50 Value: N/A
Curcumin is a natural phenolic compound with impressive antioxidant properties. Curcumin is recently proved to exert its chemopreventive effects partly through the activation of nuclear factor (erythroid-2 related) factor 2 (Nrf2) [1]. Curcumin possesses chemopreventive properties against several types of cancer, but the molecular mechanisms by which it induces apoptosis of cancer cells and inhibits cancer cell proliferation are not clearly understood.
in vitro: curcumin induced the expression of forkhead box protein O1 (FOXO1) through activation of extracellular signal-regulated kinase 1/2 signaling. Curcumin inhibited cell proliferation, which was associated with upregulation of the cyclin-dependent kinase inhibitors, p27 and p21, and downregulation of cyclin D1 [2]. Treatment of AGS and HT-29 cells with curcumin enhanced the cleavage of procaspase-3, -7, -8 and -9. Meanwhile, curcumin induced endoplasmic reticulum (ER) str
应用 酸碱指示剂，pH7.8(黄)～9.2(红棕)。显色反应测铍、锆和镁，硼酸盐和试剂。
密度 0.93
熔点 183°C
描述
产品介绍 易溶于冰乙酸，能溶于醇，不溶于醚带淡绿色荧先，溶于碱呈红棕色，加酸于碱液后变为淡黄色并析出姜黄素沉淀，溶于浓硫酸带黄红色，不溶于水。
别名 克扣明;姜黄色素;川芎内酯 B;1,7-双(4-羟基-3-甲氧基苯基)-1,6-庚二烯-3,5-二酮;(E,E)-1,7-双(4-羟基-3-甲氧基苯基)-1,6-庚二烯-3,5-二酮;Natural Yellow 3;Diferuloylmethane;Diferulylmethane;(E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
生化机理
Description:
IC50 Value: N/A
Curcumin is a natural phenolic compound with impressive antioxidant properties. Curcumin is recently proved to exert its chemopreventive effects partly through the activation of nuclear factor (erythroid-2 related) factor 2 (Nrf2) [1]. Curcumin possesses chemopreventive properties against several types of cancer, but the molecular mechanisms by which it induces apoptosis of cancer cells and inhibits cancer cell proliferation are not clearly understood.
in vitro: curcumin induced the expression of forkhead box protein O1 (FOXO1) through activation of extracellular signal-regulated kinase 1/2 signaling. Curcumin inhibited cell proliferation, which was associated with upregulation of the cyclin-dependent kinase inhibitors, p27 and p21, and downregulation of cyclin D1 [2]. Treatment of AGS and HT-29 cells with curcumin enhanced the cleavage of procaspase-3, -7, -8 and -9. Meanwhile, curcumin induced endoplasmic reticulum (ER) str
应用 酸碱指示剂，pH7.8(黄)～9.2(红棕)。显色反应测铍、锆和镁，硼酸盐和试剂。
