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英文名称 Anti-BPOZ/ABTB1
中文名称： 伸长因子结合蛋白抗体
别 名 ABTB 1; ABTB1; ABTB1_HUMAN; Ankyrin repeat and BTB (POZ) domain containing 1; Ankyrin repeat and BTB/POZ domain containing 1; Ankyrin repeat and BTB/POZ domain containing protein 1; Ankyrin repeat and BTB/POZ domain-containing protein 1; EF1ABP; Elongation factor 1A binding protein; Elongation factor 1A-binding protein; MGC20585; PP 2259; PP2259.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Horse
产品类型 一抗
研究领域 肿瘤 细胞生物 转录调节因子 表观遗传学
蛋白分子量 predicted molecular weight: 54kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human BPOZ/ABTB1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 ABTB1 is a 478 amino acid protein localized to the cytoplasm. ABTB1 contains two ANK repeats and two BTB (POZ) domains. The BTB (POZ) domain is thought to be involved in protein-protein interactions, and may indicate a role of ABTB1 in developmental processes. It has also been suggested that ABTB1 may be a mediator of the PTEN growth-suppressive signaling pathway. ABTB1 is ubiquitously expressed in all fetal tissues, with lower levels of expression found in adult heart. ABTB1 exists as four isoforms produced by alternative splicing.
Function : May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes.
Subcellular Location : Cytoplasm.
Tissue Specificity : Ubiquitously expressed in all fetal tissues examined including heart, brain, liver, and kidney. Also expressed at lower levels in both adult heart and hypertrophic heart.
Similarity : Contains 2 ANK repeats.
Contains 2 BTB (POZ) domains.
Database links : UniProtKB/Swiss-Prot: Q969K4.1
中文名称： 伸长因子结合蛋白抗体
别 名 ABTB 1; ABTB1; ABTB1_HUMAN; Ankyrin repeat and BTB (POZ) domain containing 1; Ankyrin repeat and BTB/POZ domain containing 1; Ankyrin repeat and BTB/POZ domain containing protein 1; Ankyrin repeat and BTB/POZ domain-containing protein 1; EF1ABP; Elongation factor 1A binding protein; Elongation factor 1A-binding protein; MGC20585; PP 2259; PP2259.
详细介绍：
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Horse
产品类型 一抗
研究领域 肿瘤 细胞生物 转录调节因子 表观遗传学
蛋白分子量 predicted molecular weight: 54kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human BPOZ/ABTB1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
相关资料：
产品介绍 ABTB1 is a 478 amino acid protein localized to the cytoplasm. ABTB1 contains two ANK repeats and two BTB (POZ) domains. The BTB (POZ) domain is thought to be involved in protein-protein interactions, and may indicate a role of ABTB1 in developmental processes. It has also been suggested that ABTB1 may be a mediator of the PTEN growth-suppressive signaling pathway. ABTB1 is ubiquitously expressed in all fetal tissues, with lower levels of expression found in adult heart. ABTB1 exists as four isoforms produced by alternative splicing.
Function : May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes.
Subcellular Location : Cytoplasm.
Tissue Specificity : Ubiquitously expressed in all fetal tissues examined including heart, brain, liver, and kidney. Also expressed at lower levels in both adult heart and hypertrophic heart.
Similarity : Contains 2 ANK repeats.
Contains 2 BTB (POZ) domains.
Database links : UniProtKB/Swiss-Prot: Q969K4.1
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