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英文名称Anti-ADCY6/FITC
中文名称:FITC标记的腺苷酸环化酶6抗体
别 名AC6; ACVI; ADCY 6; ADCYB; Adenylate cyclase 6; Adenylate cyclase type 6; Adenylate cyclase type VI; ATP pyrophosphate lyase 6; Ca(2+) inhibitable adenylyl cyclase; DKFZp779F075; EC 4.6.1.1; KIAA0422; ADCY6_HUMAN.
规格:100ul
说 明 书100ul
研究领域肿瘤 免疫学 信号转导 生长因子和激素 转录调节因子
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Sheep,
产品应用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量130kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ADCY6
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍background:
The membrane-bound adenylyl cyclases (ACs) represent one of the major families of effector enzymes for G protein-coupled receptors. Eight human AC isoforms (AC1 through AC4), encoded by separate genes, have been identified up to now. Most of the adenylate cyclase genes are comprised of 11-26 exons and distributed over a q6-430 kb. The majority of the adenylate cyclases previously described are expressed discretely in defined peripheral tissues, the type 4 adenylate cyclase (AC4) is apparently expressed in a variety of peripheral tissues and in the central nervous system, mainly in olfactory system. AC5 proteins are localized on photoreceptor cells and are also designated as GC1 and GC2. The AC5 protein resembles the other adenylyl cyclases in its predicted and proposed structure. AC5 resembles the type 6 (AC6) adenylyl cyclase in its amino acid sequence but becomes divergent at N and C-terminal ends. The AC5 and AC6 proteins are co-localized in most of the visual organs (photoreceptor cells) and are associated with other protein complexes. Both AC5 and AC6 enzymes play an important role in synaptic plasticity by coordinating overlapping synaptic inputs from Gs and Gi coupled receptor stimulation.
中文名称:FITC标记的腺苷酸环化酶6抗体
别 名AC6; ACVI; ADCY 6; ADCYB; Adenylate cyclase 6; Adenylate cyclase type 6; Adenylate cyclase type VI; ATP pyrophosphate lyase 6; Ca(2+) inhibitable adenylyl cyclase; DKFZp779F075; EC 4.6.1.1; KIAA0422; ADCY6_HUMAN.
详细介绍：
规格:100ul
说 明 书100ul
研究领域肿瘤 免疫学 信号转导 生长因子和激素 转录调节因子
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Sheep,
产品应用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量130kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ADCY6
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相关资料：
产品介绍background:
The membrane-bound adenylyl cyclases (ACs) represent one of the major families of effector enzymes for G protein-coupled receptors. Eight human AC isoforms (AC1 through AC4), encoded by separate genes, have been identified up to now. Most of the adenylate cyclase genes are comprised of 11-26 exons and distributed over a q6-430 kb. The majority of the adenylate cyclases previously described are expressed discretely in defined peripheral tissues, the type 4 adenylate cyclase (AC4) is apparently expressed in a variety of peripheral tissues and in the central nervous system, mainly in olfactory system. AC5 proteins are localized on photoreceptor cells and are also designated as GC1 and GC2. The AC5 protein resembles the other adenylyl cyclases in its predicted and proposed structure. AC5 resembles the type 6 (AC6) adenylyl cyclase in its amino acid sequence but becomes divergent at N and C-terminal ends. The AC5 and AC6 proteins are co-localized in most of the visual organs (photoreceptor cells) and are associated with other protein complexes. Both AC5 and AC6 enzymes play an important role in synaptic plasticity by coordinating overlapping synaptic inputs from Gs and Gi coupled receptor stimulation.
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