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标记一抗
英文名称Anti-KAL1/FITC
中文名称:FITC标记的卡尔曼综合症基因1抗体
别 名KAL; Adhesion molecule-like X-linked; ADMLX; Anosmin-1; HHA; KAL1; KALIG 1; KALIG1; Kallmann syndrome 1 sequence (anosmin 1); Kallmann syndrome interval gene 1; Kallmann syndrome protein; KALM; KALM_HUMAN; KMS.
规格:100ul
说 明 书100ul
研究领域神经生物学 信号转导 细胞骨架 细胞外基质
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Rat, Chicken, Dog, Pig, Horse, Sheep,
产品应用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量74kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human AF-6/l Afadin
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
产品介绍background:
May be an adhesion-like molecule with anti-protease activity
Function:
Has a dual branch-promoting and guidance activity, which may play an important role in the patterning of mitral and tufted cell collaterals to the olfactory cortex (By similarity). Chemoattractant for fetal olfactory epithelial cells.
Subunit:
Interacts with FGFR1; this interaction does not interfere with FGF2-binding to FGFR1. Binds heparin. Heparin may promote or interfere with KAL1-FGFR1-FGF2 complex formation depending on the sequential order of its binding to the various constituents. For instance, heparin-KAL1 interaction favors subsequent binding to pre-existing binary FGFR1-FGF2 complex, while heparin-FGF2 complex does not interact with KAL1-FGFR1.
Subcellular Location:
Cell membrane; Peripheral membrane protein. Secreted. Note=Proteolytic cleavage may release it from the cell surface into the extracellular space.
Tissue Specificity:
Expressed in the cerebellum (at protein level).
Post-translational modifications:
N-glycosylated.
中文名称:FITC标记的卡尔曼综合症基因1抗体
别 名KAL; Adhesion molecule-like X-linked; ADMLX; Anosmin-1; HHA; KAL1; KALIG 1; KALIG1; Kallmann syndrome 1 sequence (anosmin 1); Kallmann syndrome interval gene 1; Kallmann syndrome protein; KALM; KALM_HUMAN; KMS.
详细介绍：
规格:100ul
说 明 书100ul
研究领域神经生物学 信号转导 细胞骨架 细胞外基质
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Rat, Chicken, Dog, Pig, Horse, Sheep,
产品应用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量74kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human AF-6/l Afadin
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
相关资料：
产品介绍background:
May be an adhesion-like molecule with anti-protease activity
Function:
Has a dual branch-promoting and guidance activity, which may play an important role in the patterning of mitral and tufted cell collaterals to the olfactory cortex (By similarity). Chemoattractant for fetal olfactory epithelial cells.
Subunit:
Interacts with FGFR1; this interaction does not interfere with FGF2-binding to FGFR1. Binds heparin. Heparin may promote or interfere with KAL1-FGFR1-FGF2 complex formation depending on the sequential order of its binding to the various constituents. For instance, heparin-KAL1 interaction favors subsequent binding to pre-existing binary FGFR1-FGF2 complex, while heparin-FGF2 complex does not interact with KAL1-FGFR1.
Subcellular Location:
Cell membrane; Peripheral membrane protein. Secreted. Note=Proteolytic cleavage may release it from the cell surface into the extracellular space.
Tissue Specificity:
Expressed in the cerebellum (at protein level).
Post-translational modifications:
N-glycosylated.
