磷酸化丝氨酸/苏氨酸蛋白激酶II β/casein kinase IIβ抗体

英文名称  Anti-phospho-CK II beta (Ser209) 
中文名称  磷酸化丝氨酸/苏氨酸蛋白激酶II β/casein kinase IIβ抗体 
别    名  Casein Kinase 2 beta (phospho S209); p-Casein Kinase 2 beta (phospho S209); Casein Kinase 2 beta (p-S209); p-CSK2B(Ser209); phospho-CSK2B(Ser209); Casein kinase 2 beta polypeptide; casein kinase IIβ; Casein kinase II subunit beta;
详细介绍：

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浓    度  1mg/1ml 
规 格  0.1ml/100μg   
抗体来源  Rabbit  
克隆类型  polyclonal 
交叉反应  Human, Mouse, Rat, Pig, Cow   
产品类型  一抗  磷酸化抗体   
研究领域  肿瘤 细胞生物 信号转导 细胞周期蛋白 转录调节因子 激酶和磷酸酶  
蛋白分子量  predicted molecular weight: 24kDa 
性    状  Lyophilized or Liquid 
免 疫 原  KLH conjugated synthesised phosphopeptide derived from human CK II beta around the phosphorylation site of Ser209 
亚    型  IgG 
纯化方法  affinity purified by Protein A 
储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 
产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 
（石蜡切片需做抗原修复） 
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user.  
保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

相关资料：

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产品介绍 This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. [provided by RefSeq, Jul 2008].
Function : Participates in Wnt signaling (By similarity). Plays a complex role in regulating the basal catalytic activity of the alpha subunit.
Subunit : Tetramer composed of an alpha subunit, an alpha' subunit and two beta subunits. The beta subunit dimerization is mediated by zinc ions. Interacts with TCTEX1D3 (By similarity). Interacts with CD163. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation. Interacts with MUSK; mediates phosphorylation of MUSK by CK2.
Post-translational modifications : Phosphorylated by alpha subunit. 
Similarity : Belongs to the casein kinase 2 subunit beta family.
Database links : UniProtKB/Swiss-Prot: P67870.1