2017-5-4
英文名称 Anti-C8orf33
中文名称 8号染色体开放阅读框33抗体
别 名 Chromosome 8 open reading frame 33; Hypothetical protein LOC65265; UPF0488 protein C8orf33;CH033_HUMAN.
详细介绍:
相关资料:
产品介绍 Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. The C8orf33 gene product has been provisionally designated C8orf33 pending further characterization.
Similarity : Belongs to the UPF0488 family.
Database links : UniProtKB/Swiss-Prot: Q9H7E9.1
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