噻菌灵

产品编号：Y0192

英文名称：Thiabendazole

CAS号 148-79-8 

分析标准品

分子式 C10H7N3S 分子量201.25

基本信息:

密度  1.4060

熔点  304-305°C

溶解性  Soluble in ethanol (1 mg/ml), DMF (50 mg/ml), chlorinated hydrocarbons (slightly), DMSO (40 mg/ml), and water (<1 mg/ml).

描述

产品介绍  不溶于水，微溶于醇、丙酮，易溶于乙醚、氯仿。

别名  噻苯咪唑;噻苯唑;2-(1,3-噻唑-4-基)苯并咪唑;2-(4-噻唑基)苯并咪唑;2-(4-Thiazolyl)benzimidazole; 2-(thiazol-4-yl)benzimidazole; 2-(1,3-Thiazol-4-yl)benzimidazole; Mintezol; Mintesol; Omnizole;Lombristop; Thiabendazol

生化机理  Thiabendazole inhibits anaerobic respiration at the level of mitochondrial helminth-specific enzyme. It acts as a quinol-fumarate reductase (QFR) inhibitor in ,C. jejuni and H. pylori, blocking quinol oxidation to quinone. Thiabendazole suppresses egg and larval production and may inhibit the subsequent development of eggs and larvae which are passed in feces2. A proposed route of biotransformation of thiabendazole is the CYP1A2-catalyzed hydroxylation to 5-hydroxythiabendazole, which is metabolized to glucuronide and sulfate conjugates.

应用  内吸性杀菌剂。能防止多种植物的真菌病害，用于处理收获后的水果和蔬菜，可防止贮存中发生的上些病害，目前国内外已广泛应用。