1263

3,4-苯并芘标准溶液

2017-4-18

产品编号

英文名称

CAS

包装

Y0255

3,4-Benzopyrene solution

50-32-8

可根据客户要求订制

产品编号:Y0255

英文名称:3,4-Benzopyrene solution

CAS 50-32-8

5.0μg/mL,基体:甲醇

分子式 C20H12 分子量252.31

基本信息:



敏感性  对光线敏感

密度  1.0000

溶解性  不溶于水,微溶于乙醇、甲醇,溶于苯、甲苯、二甲苯、氯仿、乙醚、丙酮等。

存贮条件  阴凉干燥通风处存储。

描述

别名  ;3,4-Benzpyrene Benzo[def]chrysene Benzo[a]pyrene

应用  A polycyclic aromatic hydrocarbon (PAH), environmental pollutant and carcinogen. Used as a chemical carcinogen in experimental models of cancer. Carcinogenesis depends on its oxidation by CYP1A1 to benzo[a]pyrenediolepoxide, that forms depurinating adducts with DNA that dissociate to form abasic lesions. Benzo[a]pyrene is a ligand for the arylhydrocarbon receptor (AhR), and some of its biological effects, including the induction of CYP1A1, appear to be mediated via activation of the AhR.

 


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