2017-4-18
产品编号 |
英文名称 |
CAS号 |
包装 |
Y0255 |
3,4-Benzopyrene solution |
50-32-8 |
可根据客户要求订制 |
产品编号:Y0255
英文名称:3,4-Benzopyrene solution
CAS号 50-32-8
5.0μg/mL,基体:甲醇
分子式 C20H12 分子量252.31
基本信息:
敏感性 对光线敏感
密度 1.0000
溶解性 不溶于水,微溶于乙醇、甲醇,溶于苯、甲苯、二甲苯、氯仿、乙醚、丙酮等。
存贮条件 阴凉干燥通风处存储。
描述
别名 ;3,4-Benzpyrene Benzo[def]chrysene Benzo[a]pyrene
应用 A polycyclic aromatic hydrocarbon (PAH), environmental pollutant and carcinogen. Used as a chemical carcinogen in experimental models of cancer. Carcinogenesis depends on it′s oxidation by CYP1A1 to benzo[a]pyrenediolepoxide, that forms depurinating adducts with DNA that dissociate to form abasic lesions. Benzo[a]pyrene is a ligand for the arylhydrocarbon receptor (AhR), and some of its biological effects, including the induction of CYP1A1, appear to be mediated via activation of the AhR.
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