9号染色体开放阅读框5抗体

英文名称  Anti-C9orf5 
中文名称  9号染色体开放阅读框5抗体 
别    名  C9orf5; TM245_HUMAN; Protein CG-2; Transmembrane protein C9orf5;  
详细介绍：

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浓    度  1mg/1ml 
规 格  0.2ml/200μg    
抗体来源  Rabbit  
克隆类型  polyclonal 
交叉反应  Human, Dog, Cow, Sheep  
产品类型  一抗    
研究领域  细胞生物 免疫学  
蛋白分子量  predicted molecular weight: 101kDa 
性    状  Lyophilized or Liquid 
免 疫 原  KLH conjugated synthetic peptide derived from human C9orf5 
亚    型  IgG 
纯化方法  affinity purified by Protein A 
储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 
产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 
（石蜡切片需做抗原修复） 
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user.  
保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

相关资料：

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产品介绍 C9orf5 (chromosome 9 open reading frame 5), also known as CG2, is a 911 amino acid multi-pass membrane protein that is widely expressed and exists as four alternatively spliced isoforms. The gene encoding C9orf5 maps to human chromosome 9, which consists of about 145 million bases, represents 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
Subcellular Location : Membrane; Multi-pass membrane protein (Potential). 
Tissue Specificity : Widely expressed.
Similarity : Belongs to the UPF0118 (TMEM245) family.
Database links : UniProtKB/Swiss-Prot: Q9H330.2