磷酸化腺苷单磷酸活化蛋白激酶α2抗体
2017-5-4
英文名称 Anti-phospho-AMPK alpha 2 (Ser345)
中文名称 磷酸化腺苷单磷酸活化蛋白激酶α2抗体
别 名 AMPK alpha 2 (phospho S345); p-AMPK2(phospho S345); 5'-AMP-activated protein kinase catalytic subunit alpha-2; AAPK2_HUMAN; AMP activated protein kinase alpha 2 catalytic subunit; AMPK 2; AMPK alpha 2 chain; AMPK subunit alpha-2; ; AMPKalpha2; PRKAA 2; PRKAA; PRKAA2; Protein kinase AMP activated alpha 2 catalytic subunit.
浓 度 1mg/1ml
规 格 0.1ml/100μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Mouse, Rat
产品类型 一抗 磷酸化抗体
研究领域 肿瘤 细胞生物 信号转导 转录调节因子 激酶和磷酸酶 新陈代谢
蛋白分子量 predicted molecular weight: 62kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human AMPK alpha 2 around the phosphorylation site of Ser345
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.
Similarity : Belongs to the protein kinase superfamily.
CAMK Ser/Thr protein kinase family.
SNF1 subfamily.
Contains 1 protein kinase domain.
中文名称 磷酸化腺苷单磷酸活化蛋白激酶α2抗体
别 名 AMPK alpha 2 (phospho S345); p-AMPK2(phospho S345); 5'-AMP-activated protein kinase catalytic subunit alpha-2; AAPK2_HUMAN; AMP activated protein kinase alpha 2 catalytic subunit; AMPK 2; AMPK alpha 2 chain; AMPK subunit alpha-2; ; AMPKalpha2; PRKAA 2; PRKAA; PRKAA2; Protein kinase AMP activated alpha 2 catalytic subunit.
详细介绍：
浓 度 1mg/1ml
规 格 0.1ml/100μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Mouse, Rat
产品类型 一抗 磷酸化抗体
研究领域 肿瘤 细胞生物 信号转导 转录调节因子 激酶和磷酸酶 新陈代谢
蛋白分子量 predicted molecular weight: 62kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human AMPK alpha 2 around the phosphorylation site of Ser345
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
相关资料：
产品介绍 Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.
Similarity : Belongs to the protein kinase superfamily.
CAMK Ser/Thr protein kinase family.
SNF1 subfamily.
Contains 1 protein kinase domain.
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