规格:100ug
说 明 书100ug
研究领域发育生物学 染色质和核信号
抗体来源Rabbit
克隆类型Polyclonal
交叉反应
产品应用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量24kDa
性 状Lyophilized or Liquid
浓 度2mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from mouse Nucleoplasmin 2
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相关资料:
产品介绍background:
NPM2 (Nucleophosmin/Nucleoplasmin 2) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and enzyme binding. An important paralog of this gene is NPM1.
Function:
Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization.
Subunit:
Homopentamer, when bound to H2A-H2B dimers only. Homodecamer of two stacked pentamers, when bound to H2A-H2B dimers and H3-H4 tetramers simultaneously (By similarity).
Subcellular Location:
Nucleus. Found in the oocyte nucleus before nuclear membrane breakdown, after which it is redistributed to the cytoplasm.