FITC标记的蛋白激酶B3
2017-5-3
英文名称Anti-AKT3/FITC
中文名称:FITC标记的蛋白激酶B3
别 名AKT3 kinase; DKFZP434N0250; PKB Gamma; PKBG; PRKBG; Protein Kinase AKT3; Protein Kinase B Gamma; RAC gamma; RAC Gamma Serine/Threonine Protein Kinase; RACPK Gamma; Serine threonine protein kinase Akt 3; Serine Threonine Protein Kinase AKT3; STK 2; STK2; V akt murine thymoma viral oncogene homolog 3 protein kinase B gamma; VAKT Murine Thymoma Viral Oncogene Homolog 3; AKT3_HUMAN.
详细介绍:
规格:100ul
说 明 书100ul
研究领域肿瘤 细胞生物 免疫学 信号转导 转录调节因子 激酶和磷酸酶
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit, Sheep,
产品应用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量56kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human AKT3
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相关资料:
产品介绍background:
Akt, protein kinase B (PKB), is a serine/threonine kinase which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activate phosphtidylinositol 3 kinase (PI 3 kinase). The major activity of Akt/PKB is to mediate cell survival. Akt/PKB is also believed to be a critical factor in the genesis of cancer as the tumor suppressor PTEN was found to antagonise PI3 kinase and Akt/PKB kinase activity. There are 3 known isoforms of this enzyme in mammalian cells (1/alpha, 2/beta and 3/gamma). IGF1 leads to the activation of AKT3, which may play a role in regulating cell survival. It is capable of phosphorylating several known proteins.
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