迷迭香酸

产品编号	英文名称	CAS号	包装
Y3744	Rosmarinic acid	20283-92-5	可根据客户要求订制

产品编号：Y3744

英文名称：Rosmarinic acid
CAS号：20283-92-5
分析标准品,≥97%
分子式 C18H16O8 分子量360.31

基本信息:

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熔点 171-175°C
溶解性 Soluble in water (100 mM), ethanol (~25 mg/ml), DMSO (~25 mg/ml), DMF (~25 mg/ml), and PBS (pH 7.2) (~15 mg/ml).
描述
别名 迷迭香酸;(R)-O-(3,4-Dihydroxycinnamoyl)-3-(3,4- dihydroxyphenyl)lactic acid 3,4-Dihydroxycinnamic acid (R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl ester
生化机理 Rosmarinic Acid is a phenylpropanoid isolated from Labiatae herbs. The compound exhibits antiinflammatory activity and inhibits the proliferation of murine mesangial cells. Rosmarinic Acid has been shown to dose dependently inhibit migration, adhesion, and invasion of Ls174-T human colon carcinoma cells. Rosmarinic Acid has been documented to increase the melanin content in B16 melanoma cells through activation of protein kinase A. In the same study rosmarinic acid induced the phosphorylation of CRE-binding protein (CREB) and activated cAMP response element (CRE). In the classical complement pathway Rosmarinic Acid inhibited C3-convertase. It also has shown to be an activator of GPR35.
应用 An activator of GPR35.