青蒿素
2017-4-28
产品编号
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英文名称
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CAS号
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包装
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Y3880
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Artemisinin
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63968-64-9
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可根据客户要求订制
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产品编号:Y3880
英文名称:Artemisinin
CAS号:63968-64-9
分析标准品
分子式 C15H22O5 分子量282.33
基本信息:
旋光率 75 ° (C=0.5, MeOH)
密度1.24
熔点 156-157°C
溶解性 Soluble in methanol, ethanol (24 mg/ml) at 25 °C, DMF, DMSO (57 mg/ml) at 25 °C, acetone, chloroform (25 mg/ml), dichloromethane, and ethyl acetate; almost insoluble in water.
描述
产品介绍 Artemisinin用于治疗耐多药的恶性疟疾菌株。
别名 黄花蒿素;(3R,5aS,6R,8aS,9R,10S,12R,12aR)-十氢-3,6,9-三甲基-3,12-桥氧-12H-吡喃并[4,3-j]-1,2-苯并二塞平-10-酮;Arteannuin; Qinghaosu;[3R-(3R,5aS,6S,8aS,9R,10R,12S,12aR**)]-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-one
生化机理 Artemisinin is a powerful antimalarial agent. Artemisinin inhibits angiogenesis by down-regulating HIF-1α and VEGF expression in mouse embryonic stem cells. Artemisinin crosses the blood-brain barrier and is an inhibitor of human NOS2 (iNOS).
应用 An antimalarial agent that inhibits VEGF expression and NOS2.