白屈菜红碱

产品编号	英文名称	CAS号	包装
Y3705	Chelerythrine chloride	34316-15-9	可根据客户要求订制

产品编号：Y3705

英文名称：Chelerythrine chloride　

CAS号：34316-15-9
分析标准品,>98%  
分子式 C21H18ClNO4 分子量383.83  

基本信息:

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熔点   195-205°C
描述  
别名   白屈菜赤碱;白屈菜季铵碱;1,2-Dimethoxy-N-methyl-[1,3]benzodioxolo[5,6-c]phenanthridinium chloride
生化机理  
Chelerythrine is potent, cell-permeable inhibitor of protein kinase C (IC50 = 660 nM). competitive with respect to the phosphate acceptor and non-competitive with respect to ATP. Chelerythrine has a wide range of biological activities, including antiplatelet, anti-inflammatory, antibacterial and antitumor effects. Activates MAPK pathways, independent of PKC inhibition. Inhibits binding of BclXL to Bak (IC50 = 1.5 μM) or Bad proteins and stimulates apoptosis.  
应用   对某些真菌、细菌和病毒有抑制作用，但对神经、心脏等有毒害，可引起麻痹、心脏抑制，甚至导致死亡。